Workshop on

Parameter Estimation for Dynamical Systems

June 8-10, 2009

EURANDOM, Eindhoven, The Netherlands

Programme & Abstracts| Speakers & Participants | Registration | Practical Information | Useful links


Systems of ordinary differential equations (ODEs) play an important role in modelling various phenomena that arise in fields as diverse as physics, biology, engineering, chemistry, meteorology, pharmacology and others. In many cases these systems are nonlinear, which means that in general no analytic solution exists and one has to rely on numerical solutions. Such systems usually depend on constants, or parameters in statistical terminology. For instance, in biomolecular applications these parameters describe interaction rates and initial concentrations of various molecules relevant to a given biomolecular process. In order to obtain a model useful in practice, it is critical to know these parameters. Since in most cases they are not known beforehand and cannot be measured directly in the lab, they have to be inferred based on measurements of various variables related to the process at hand. However, measurements in general are subject to some measurement error. It also might be the case that not all relevant variables are observed due to technical complications, high cost of experiments, and other reasons. Typically, problems are complicated further by the fact that the dimensions of both the ODE system as well as the parameter space are high, while data are relatively scarce. Hence estimation of parameters of ODE systems is a challenging problem that lies at an intersection of several theoretical and applied fields. The aim of the workshop is to provide a meeting place for researchers in the area, who will review different methods used to tackle the problem, assess the achieved progress, and identify future research directions.


Nicolas Brunel, L’université d’Évry, Évry
Dave Campbell, Simon Fraser University, Vancouver
Piet Hemker, CWI, Amsterdam

Dave Lunn, MRC Biostatistics Unit Cambridge
Kim McAuley, Queen’s University, Kingston
Jim Ramsay, McGill University, Montreal
Eberhard Voit, Georgia Institute of Technology, Atlanta
Victor Zavala, Argonne National Laboratory, Argonne


Preliminary PROGRAMME

Monday June 8, 2009


Tuesday June 9, 2009


Wednesday June 10, 2009

10.00 - 11.00 Registration     10.00 - 10.30 G. Holtrop
11.00 - 11.15 Opening 10.30 - 11.15 J. Ramsay 10.30 - 11.00 T. Maiwald
11.15 - 12.00 D. Lunn 11.15 - 12.00 D. Campbell 11.00 - 11.15 Break
12.00 - 14.00 Lunch 12.00 - 14.00 Lunch 11.15 - 12.00 E. Voit
14.00 - 14.45 N. Brunel 14.00 - 14.45 V. Zavala 12.00 - 12.10 Closing
14.45 - 15.30 P. Hemker 14.45 - 15.30 K. McAuley 12.10 Lunch
15.30 - 16.00 Break 15.30 - 16.00 Break    
16.00  -16.30 A. Bhadra 16.00 - 16.30 N. Filmann    
16.30 - 17.00 Postersession 16.30 - 17.00 D. Salazar    
17.00 - 17.30 A. Raue 17.00 - 18.00 Discussion    
17.30 - 18.00 J. Nĕmcova        
19.00 Dinner        






Participants will be given the opportunity of giving talks on their own research. Please mail the title and abstract of your talk to Shota Gugushvili ( The deadline for abstract submission is May 15, 2009. A notification of acceptance will be sent by May 29, 2009.


Please register by filling in the FORM. There is no closing date for registration, but the number of places is limited. There is no registration fee.


Conference Location

The workshop location is EURANDOM, Den Dolech 2, 5612 AZ Eindhoven, Laplace Building, 1st floor, LG 1.105.

EURANDOM is located on the campus of  Technische Universiteit Eindhoven in the Laplace building (marked with LG on the map). The building is at 15 minutes walking distance from the Eindhoven railway station (take the northern exit and walk in the north-eastern direction until you reach a crossing at Fellenoord. The campus is located on the other side of that street).

For travel information to Eindhoven, please check


For the invited speakers Hotel Queen is reserved. Please indicate your arrival and departure dates on the registration form.

For participants, there is a possibility to stay at Sandton Hotel Eindhoven City Centre (a reduced rate of 89 Euros* is applicable). Please indicate your arrival and departure dates on the registration form.

For private bookings we suggest consulting the webpage of VVV Eindhoven.

* single room, breakfast included, excluding the tourist tax 3,50 Euro per night.


On all three days free lunches are offered to the participants. Please indicate your attendance on the registration form. On Monday evening there will be a workshop dinner. Indicate your attendance on the registration form. For non-invitees an amount of 35 Euros is requested, to be paid at the registration desk in cash (preferably an exact amount in Euros).


For more information please contact Mrs. Lucienne Coolen, the workshop officer of  EURANDOM, at coolen 'at'


Chris Klaassen, Universiteit van Amsterdam & EURANDOM, c.a.j.klaassen'at'

Shota Gugushvili, EURANDOM, gugushvili'at'

Bart Bakker, Philips Research, bart.bakker'at'




Participants of this workshop might be also interested in the workshop on "Statistical Methods for Dynamic System Models", Vancouver, Canada, June 4-6, 2009.

The organisers would like to acknowledge the contributions of the following organisations                                      KNAW homepage KNAW

Last up-dated 04-06-09
This page is maintained by
Lucienne Coolen